胡锦辉 返回专家列表


       胡锦辉,复旦大学医学博士, 美国NIH博士后,副主任技师,美国免疫学家学会会员(America Association of Immunologists, AAI),中华医学会上海分会检验学会免疫学组成员,International Immunopharmacology, Scientific Reports杂志审稿人。

       参与美国NIH课题一项,中国国家自然科学基金项目5项,主持上海市浦东科委及复旦大学妇产科医院重点实验室开放课题各一项。第一作者或通讯作者发表SCI论著6篇。有多年医院检验科学习工作经历,二年科室副主任经验,参与组织实施科室等级评审、临床检验质量控制。

       2013年九月至今在美国NIH/NCI从事博士后研究,主要从事细胞与分子免疫学研究,目前的研究涉及T细胞分化调控,T细胞抗肿瘤效应的诱导及改进。

       SELECTED PUBLICATION
       1. #Sabatino, M. et al. Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies. Blood 128, 519-528 (2016).
       2. Ji, Y. et al. miR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic gammac cytokines. Proc Natl Acad Sci U S A 112, 476-481 (2015).
       3. Hu, J., Zhang, Y., Liu, X., Wei, L. & Zhang, D. Relationship between certain T helper cytokines and ANA staining: who is the helper? Int Immunopharmacol 24, 208-210 (2015).
       4. *Qiu, C. et al. GM-CSF induces cyclin D1 expression and proliferation of endothelial progenitor cells via PI3K and MAPK signaling. Cell Physiol Biochem 33, 784-795 (2014).
       5. Hu, J. et al. U87MG glioma cells overexpressing IL-17 acclerate early-stage growth in vivo and cause a higher level of CD31 mRNA expression in tumor tissues. Oncol Lett 6, 993-999 (2013).
       6. Hu, J. et al. Th17-relevant cytokines vary with sera of different ANA staining patterns. Int Immunopharmacol 15, 679-684 (2013).
       7. Li, M. et al. MRSA epidemic linked to a quickly spreading colonization and virulence determinant. Nat Med 18, 816-819 (2012).
       8. Hu, J., Mao, Y., Li, M. & Lu, Y. The profile of Th17 subset in glioma. Int Immunopharmacol 11, 1173-1179 (2011).
       9. Gu, F.M. et al. IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma. Mol Cancer 10, 150 (2011).
       10. Li, M. et al. Comparative analysis of virulence and toxin expression of global community-associated methicillin-resistant Staphylococcus aureus strains. J Infect Dis 202, 1866-1876 (2010).
       11. 胡锦辉,邱潮林,华玲,谢秋华,何小雪,沈振华,胡珺。IL-17真核表达载体构建及其在胶质瘤细胞株U87MG中的表达与筛选。现代免疫学,2013.33(2): 107-112
       12. 胡锦辉,毕胜利,吕元。Th17——正逐步获得深入研究。中国免疫学杂志2012.Apr;28(4)372-378
       13. 胡锦辉,毕胜利,沈振华,李敏,宋燕,杜昕,关明,吕元。U87MG培养上清致Naïve CD4+ T细胞分化为Th2降低。免疫学杂志 2012.Apr;28(4)300-304